Detection of mutations in gyrB using denaturing

0 Comments
long-qt-syndrome

Detection of mutations in gyrB using denaturing extreme effectivity liquid chromatography (DHPLC) amongst Salmonella enterica serovar Typhi and Paratyphi A.  Fluoroquinolone resistance is mediated by mutations inside the quinolone-resistance determining space (QRDR) of the topoisomerase genes. Denaturing extreme effectivity liquid chromatography (DHPLC) was evaluated for detection of clinically very important mutations in gyrB amongst Salmonella. […]