Development of a new DHPLC assay


Growth of a brand new DHPLC assay for genotyping UGT1A (TA)n polymorphism related to Gilbert’s syndrome. BACKGROUND Gilbert’s syndrome is the commonest hereditary dysfunction of bilirubin metabolism. The causative mutation in Caucasians is sort of solely a (TA) dinucleotide insertion within the UGT1A1 promoter. Affected people are homozygous for the variant promoter and have 7 TA repeats […]